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Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes

We have recently shown that a single injection of mature, antigen-pulsed, human dendritic cells (DCs) rapidly elicits CD4(+) and CD8(+) T-cell immunity in vivo. The DCs were pulsed with 2 foreign proteins, keyhole limpet hemocyanin (KLH) and tetanus toxoid (TT), as well as an HLA A2.1-restricted inf...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Dhodapkar, Madhav V., Krasovsky, Joseph, Steinman, Ralph M., Bhardwaj, Nina
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377466/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10727452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9051
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