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Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy

Glycogen synthase kinase 3 (GSK3) is a multifunctional serine/threonine kinase that participates in numerous signalling pathways involved in diverse physiological processes. Several of these pathways are implicated in disease pathogenesis, which has prompted efforts to develop GSK3-specific inhibito...

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Detalhes bibliográficos
Main Authors: Wang, Zhong, Smith, Kevin S., Murphy, Mark, Piloto, Obdulio, Somervaille, Tim C. P., Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084721/
https://ncbi.nlm.nih.gov/pubmed/18806775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07284
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