Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain

BACKGROUND: Persistent anxiety-like symptoms may have an inflammatory-related pathophysiology. Our previous work using repeated social defeat (RSD) in mice showed that recruitment of peripheral myeloid cells to the brain is required for the development of anxiety. Here, we aimed to determine if 1) R...

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Autori principali: Wohleb, Eric S., McKim, Daniel B., Shea, Daniel T., Powell, Nicole D., Tarr, Andrew J., Sheridan, John F., Godbout, Jonathan P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084643/
https://ncbi.nlm.nih.gov/pubmed/24439304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.11.029
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