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Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior

HIGHLIGHTS: Psychological stress activates neuroendocrine pathways that alter immune responses. Stress-induced alterations in microglia phenotype and monocyte priming leads to aberrant peripheral and central inflammation. Elevated pro-inflammatory cytokine levels caused by microglia activation and r...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Wohleb, Eric S., McKim, Daniel B., Sheridan, John F., Godbout, Jonathan P.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300916/
https://ncbi.nlm.nih.gov/pubmed/25653581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00447
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