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Locating the Route of Entry and Binding Sites of Benzocaine and Phenytoin in a Bacterial Voltage Gated Sodium Channel

Sodium channel blockers are used to control electrical excitability in cells as a treatment for epileptic seizures and cardiac arrhythmia, and to provide short term control of pain. Development of the next generation of drugs that can selectively target one of the nine types of voltage-gated sodium...

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Detalles Bibliográficos
Main Authors: Martin, Lewis J., Corry, Ben
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084639/
https://ncbi.nlm.nih.gov/pubmed/24992293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003688
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