Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by ex Vivo Granulocyte-Macrophage Colony-stimulating Factor Gene Transfer()

Granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transduced, irradiated tumor vaccines induce potent, T-cell-mediated antitumor immune responses in preclinical models. We report the initial results of a Phase I trial evaluating this strategy for safety and the induction of immune respo...

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Bibliografiske detaljer
Main Authors: Simons, Jonathan W., Jaffee, Elizabeth M., Weber, Christine E., Levitsky, Hyam I., Nelson, William G., Carducci, Michael A., Lazenby, Audrey J., Cohen, Lawrence K., Finn, Christy C., Clift, Shirley M., Hauda, Karen M., Beck, Lisa A., Leiferman, Kristen M., Owens, Albert H., Piantadosi, Steven, Dranoff, Glenn, Mulligan, Richard C., Pardoll, Drew M., Marshall, Fray F.
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084516/
https://ncbi.nlm.nih.gov/pubmed/9108457
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