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An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2–dominated inflammatory response

In schistosomiasis, chronic parasite egg–induced granuloma formation can lead to tissue destruction and fibrosis, which causes much of the morbidity and mortality associated with this disease. Here we show the importance of IL-13 in the pathogenesis of schistosomiasis, and demonstrate, perhaps for t...

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Bibliographic Details
Main Authors: Chiaramonte, Mónica G., Donaldson, Debra D., Cheever, Allen W., Wynn, Thomas A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC408441/
https://ncbi.nlm.nih.gov/pubmed/10491413
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