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Monoclonal antibodies raised against Guillain-Barré syndrome–associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations

Guillain-Barré syndrome and its variant, Miller-Fisher syndrome, are acute, postinfectious, autoimmune neuropathies that frequently follow Campylobacter jejuni enteritis. The pathogenesis is believed to involve molecular mimicry between sialylated epitopes on C. jejuni LPSs and neural gangliosides....

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Goodyear, Carl S., O’Hanlon, Graham M., Plomp, Jaap J., Wagner, Eric R., Morrison, Ian, Veitch, Jean, Cochrane, Lynne, Bullens, Roland W. M., Molenaar, Peter C., Conner, Joe, Willison, Hugh J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10491405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6837
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