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Inhibition of TGF-β(3) restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies

Preeclampsia, the major cause of maternal morbidity and mortality in developed countries, is associated with abnormalities of placenta function due to shallow invasion of the maternal decidua by trophoblasts. Data suggest that TGF-β may play a role in inhibiting trophoblast outgrowth or invasion, or...

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Main Authors: Caniggia, Isabella, Grisaru-Gravnosky, Sorina, Kuliszewsky, Maciej, Post, Martin, Lye, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC408387/
https://ncbi.nlm.nih.gov/pubmed/10377170
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