Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures

Annexin II (AXII), a calcium-dependent phospholipid-binding protein, has been recently found to be an osteoclast (OCL) stimulatory factor that is also secreted by OCLs. In vitro studies showed that AXII induced OCL formation and bone resorption. However, the mechanism of action by which AXII acts as...

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Pubblicato in:	J Clin Invest
Autori principali:	Menaa, Cheikh, Devlin, Rowena D., Reddy, Sakamuri V., Gazitt, Yair, Choi, Sun Jin, Roodman, G. David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1999
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6374
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