Radiosynthesis and validation of (18)F-FP-CMT, a phenyltropane with superior properties for imaging the dopamine transporter in living brain

To date there is no validated, (18)F-labeled dopamine transporter (DAT) radiotracer with a rapid kinetic profile suitable for preclinical small-animal positron emission tomography (PET) studies in rodent models of human basal ganglia disease. Herein we report radiosynthesis and validation of the phe...

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Detalhes bibliográficos
Main Authors: Cumming, Paul, Maschauer, Simone, Riss, Patrick J, Tschammer, Nuska, Fehler, Stefanie K, Heinrich, Markus R, Kuwert, Torsten, Prante, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083377/
https://ncbi.nlm.nih.gov/pubmed/24714035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.63
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