Renin angiotensin system modulates mTOR pathway through AT2R in HIVAN

Mammalian target of rapamycin (mTOR) has been reported to contribute to the development of HIV-associated nephropathy (HIVAN). We hypothesized that HIV may be activating renal tissue mTOR pathway through renin angiotensin system (RAS) via Angiotensin Receptor Type II receptor (AT2R). Renal tissues o...

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Detalhes bibliográficos
Main Authors: Rai, Partab, Lederman, Rivka, Haque, Shabirul, Rehman, Shabina, Kumar, Viki, Sataranatrajan, Kavithalakshmi, Malhotra, Ashwani, Kasinath, Balakuntalam S., Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083194/
https://ncbi.nlm.nih.gov/pubmed/24768585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2014.04.004
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