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Rituximab efficiently depletes increased CD20 expressing T cells in multiple sclerosis patients()

In multiple sclerosis (MS()) B cell depleting therapy using monoclonal anti-CD20 antibodies, including rituximab (RTX) and ocrelizumab (OCR), effectively reduces disease activity. Based on indirect evidence, it is generally believed that elimination of the antigen presenting capabilities and antigen...

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Hlavní autoři: Palanichamy, Arumugam, Jahn, Sarah, Nickles, Dorothee, Derstine, Mia, Abounasr, Aya, Hauser, Stephen L., Baranzini, Sergio E., Leppert, David, von Büdingen, H.-Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082756/
https://ncbi.nlm.nih.gov/pubmed/24928997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400118
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