Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

Alternative RNA splicing (AS) regulates proteome diversity, including isoform-specific expression of several pluripotency genes. Here, we integrated global gene expression and proteomic analyses and identified a molecular signature suggesting a central role for AS in maintaining human pluripotent st...

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Hauptverfasser: Lu, Yu, Loh, Yuin-Han, Li, Hu, Cesana, Marcella, Ficarro, Scott B., Parikh, Jignesh R., Salomonis, Nathan, Toh, Cheng-Xu Delon, Andreadis, Stelios T., Luckey, C. John, Collins, James J., Daley, George Q., Marto, Jarrod A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082735/
https://ncbi.nlm.nih.gov/pubmed/24813856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.04.002
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