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In silico Analysis and Experimental Verification of OSR1 Kinase - Peptide Interaction
The oxidative-stress-responsive kinase 1 (OSR1) and the STE20/SPS1-related proline/alanine-rich kinase (SPAK) are key enzymes in a signaling cascade regulating the activity of Na(+)-K(+)-2Cl(−) cotransporters (NKCC1-2) and Na(+)-Cl(−) cotransporter (NCC). Both kinases have a conserved carboxyl-termi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4082687/ https://ncbi.nlm.nih.gov/pubmed/24821279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2014.05.001 |
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