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Kinase regulation of Na(+) −K(+) −2Cl(−) cotransport in primary afferent neurons
The Na(+) −K(+) −2Cl(−) cotransporter NKCC1 is expressed in sensory neurons where it accumulates intracellular Cl(−) and facilitates primary afferent depolarization. Depolarization of primary afferent fibre terminals interferes with the gating of incoming sensory signals to the spinal cord. The cotr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988503/ https://ncbi.nlm.nih.gov/pubmed/20498230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.190769 |
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