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Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma

Asthma, a family of airway disorders characterized by airway inflammation, has an increasing incidence worldwide. Platelet-activating factor (PAF) may play a role in the pathophysiology of asthma. Its proinflammatory actions are antagonized by PAF acetylhydrolase. A missense mutation (V279F) in the...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Stafforini, Diana M., Numao, Toshio, Tsodikov, Alexander, Vaitkus, Darius, Fukuda, Takeshi, Watanabe, Naoto, Fueki, Naoto, McIntyre, Thomas M., Zimmerman, Guy A., Makino, Sohei, Prescott, Stephen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10194471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5574
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