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Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma

Asthma, a family of airway disorders characterized by airway inflammation, has an increasing incidence worldwide. Platelet-activating factor (PAF) may play a role in the pathophysiology of asthma. Its proinflammatory actions are antagonized by PAF acetylhydrolase. A missense mutation (V279F) in the...

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Detalhes bibliográficos
Main Authors: Stafforini, Diana M., Numao, Toshio, Tsodikov, Alexander, Vaitkus, Darius, Fukuda, Takeshi, Watanabe, Naoto, Fueki, Naoto, McIntyre, Thomas M., Zimmerman, Guy A., Makino, Sohei, Prescott, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408260/
https://ncbi.nlm.nih.gov/pubmed/10194471
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