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A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging

Cellular senescence is a stable proliferation arrest associated with an altered secretory pathway, the senescence-associated secretory phenotype. However, cellular senescence is initiated by diverse molecular triggers, such as activated oncogenes and shortened telomeres, and is associated with varie...

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Detalhes bibliográficos
Main Authors: Nelson, David M., McBryan, Tony, Jeyapalan, Jessie C., Sedivy, John M., Adams, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082585/
https://ncbi.nlm.nih.gov/pubmed/24647599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9637-0
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