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Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage–induced apoptosis

To evaluate the role of ceramide (Cer) in apoptosis signaling, we examined Cer formation induced by CD95, etoposide, or γ-radiation (IR) in relation to caspase activation and mitochondrial changes in Jurkat T cells. The Cer response to all three stimuli was mapped in between caspases sensitive to be...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Tepper, Annemiek D., de Vries, Evert, van Blitterswijk, Wim J., Borst, Jannie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10194469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5457
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