Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology

Apoptosis is generally accompanied by a late phase of ceramide (Cer) production, the significance of which is unknown. This study describes a previously unrecognized link between Cer accumulation and phosphatidylserine (PS) exposure at the cell surface, a characteristic of the execution phase of apo...

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Главные авторы: Tepper, Annemiek D., Ruurs, Paula, Wiedmer, Therese, Sims, Peter J., Borst, Jannie, van Blitterswijk, Wim J.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2000
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185573/
https://ncbi.nlm.nih.gov/pubmed/10893264
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