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Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line.

The epsilon 4 allele of apolipoprotein E (apoE) is a major risk factor for Alzheimer disease, suggesting that apoE may directly influence neurons in the aging brain. Recent data suggest that apoE-containing lipoproteins can influence neurite outgrowth in an isoform-specific fashion. The neuronal med...

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Detalhes bibliográficos
Main Authors: Holtzman, D M, Pitas, R E, Kilbridge, J, Nathan, B, Mahley, R W, Bu, G, Schwartz, A L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC40825/
https://ncbi.nlm.nih.gov/pubmed/7568158
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