Design, Synthesis and Bio-evaluation of an EphA2-based Targeted Delivery System

We recently described a new targeted delivery system based on specific EphA2 receptor targeting peptides conjugated with the chemotherapeutic agent paclitaxel. In this manuscript we investigate the chemical determinants responsible for the stability and degradation of these agents in plasma. Introdu...

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Main Authors: Barile, Elisa, Wang, Si, Das, Swadesh K., Noberini, Roberta, Dahl, Russell, Stebbins, John L., Pasquale, Elena B., Fisher, Paul B., Pellecchia, Maurizio
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082471/
https://ncbi.nlm.nih.gov/pubmed/24677792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201400067
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