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Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia

To determine when patients with incomplete responses on second-line tyrosine kinase inhibitor (2TKI) therapy should consider alternative treatment, we analyzed the outcome of 113 patients receiving nilotinib (n = 43) or dasatinib (n = 70) after imatinib failure. After 12 months of 2TKI therapy, pati...

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Detaylı Bibliyografya
Asıl Yazarlar: Tam, Constantine S., Kantarjian, Hagop, Garcia-Manero, Guillermo, Borthakur, Gautam, O'Brien, Susan, Ravandi, Farhad, Shan, Jenny, Cortes, Jorge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082324/
https://ncbi.nlm.nih.gov/pubmed/18492956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-141580
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