Failure to achieve a complete hematologic response at the time of a major cytogenetic response with second-generation tyrosine kinase inhibitors is associated with a poor prognosis among patients with chronic myeloid leukemia in accelerated or blast phase

Second-generation tyrosine kinase inhibitors are effective in Philadelphia chromosome–positive (Ph(+)) acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML). Occasionally, patients with Ph(+) ALL, or accelerated phase (AP) or blast phase (BP) CML achieve a major cytogenetic response...

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Detalhes bibliográficos
Main Authors: Fava, Carmen, Kantarjian, Hagop M., Jabbour, Elias, O'Brien, Susan, Jain, Nitin, Rios, Mary Beth, Garcia-Manero, Guillermo, Ravandi, Farhad, Verstovsek, Srdan, Borthakur, Gautam, Shan, Jianqin, Cortes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081366/
https://ncbi.nlm.nih.gov/pubmed/19282457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184960
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