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Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism

The aim of the study was to assess the relative control of insulin secretion rate (ISR) by calcium influx and signaling from cytochrome c in islets where, as in diabetes, the metabolic pathways are impaired. This was achieved either by culturing isolated islets at low (3 mm) glucose or by fasting ra...

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Hlavní autoři: Rountree, Austin M., Neal, Adam S., Lisowski, Mark, Rizzo, Norma, Radtke, Jared, White, Sarah, Luciani, Dan S., Kim, Francis, Hampe, Christiane S., Sweet, Ian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081948/
https://ncbi.nlm.nih.gov/pubmed/24841202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556050
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