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The Epigenetic Drug 5-Azacytidine Interferes with Cholesterol and Lipid Metabolism

DNA methylation and histone acetylation inhibitors are widely used to study the role of epigenetic marks in the regulation of gene expression. In addition, several of these molecules are being tested in clinical trials or already in use in the clinic. Antimetabolites, such as the DNA-hypomethylating...

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Autori principali: Poirier, Steve, Samami, Samaneh, Mamarbachi, Maya, Demers, Annie, Chang, Ta Yuan, Vance, Dennis E., Hatch, Grant M., Mayer, Gaétan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081918/
https://ncbi.nlm.nih.gov/pubmed/24855646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563650
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