Non-Selective Cation Channels Mediate Chloroquine-Induced Relaxation in Precontracted Mouse Airway Smooth Muscle

Bitter tastants can induce relaxation in precontracted airway smooth muscle by activating big-conductance potassium channels (BKs) or by inactivating voltage-dependent L-type Ca(2+) channels (VDLCCs). In this study, a new pathway for bitter tastant-induced relaxation was defined and investigated. We...

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Detalhes bibliográficos
Main Authors: Zhang, Ting, Luo, Xiao-Jing, Sai, Wen-Bo, Yu, Meng-Fei, Li, Wen-Er, Ma, Yun-Fei, Chen, Weiwei, Zhai, Kui, Qin, Gangjian, Guo, Donglin, Zheng, Yun-Min, Wang, Yong-Xiao, Shen, Jin-Hua, Ji, Guangju, Liu, Qing-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081631/
https://ncbi.nlm.nih.gov/pubmed/24992312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101578
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