Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

Interleukin (IL)-13 is a pleiotropic cytokine produced in large quantities by activated CD4(+) Th2 lymphocytes. To define further its potential in vivo effector functions, the Clara cell 10-kDa protein promoter was used to express IL-13 selectively in the lung, and the phenotype of the resulting tra...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Zhu, Zhou, Homer, Robert J., Wang, Zhonde, Chen, Qingsheng, Geba, Gregory P., Wang, Jingming, Zhang, Yong, Elias, Jack A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC408149/
https://ncbi.nlm.nih.gov/pubmed/10079098
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars