Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils

Activation of leukocytes by proinflammatory stimuli selectively initiates intracellular signal transduction via sequential phosphorylation of kinases. Lipopolysaccharide (LPS) stimulation of human neutrophils is known to result in activation of p38 mitogen-activated protein kinase (MAPk); however, t...

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Hauptverfasser: Nick, Jerry A., Avdi, Natalie J., Young, Scott K., Lehman, Lisa A., McDonald, Patrick P., Frasch, S. Courtney, Billstrom, Marcella A., Henson, Peter M, Johnson, Gary L., Worthen, G. Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408145/
https://ncbi.nlm.nih.gov/pubmed/10079106
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