Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils

Activation of leukocytes by proinflammatory stimuli selectively initiates intracellular signal transduction via sequential phosphorylation of kinases. Lipopolysaccharide (LPS) stimulation of human neutrophils is known to result in activation of p38 mitogen-activated protein kinase (MAPk); however, t...

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Main Authors: Nick, Jerry A., Avdi, Natalie J., Young, Scott K., Lehman, Lisa A., McDonald, Patrick P., Frasch, S. Courtney, Billstrom, Marcella A., Henson, Peter M, Johnson, Gary L., Worthen, G. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408145/
https://ncbi.nlm.nih.gov/pubmed/10079106
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