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Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d(-/-) cones

PrBP/δ, encoded by the Pde6d gene, is an isoprenyl-binding protein that regulates trafficking of isoprenylated proteins, such as PDE6 and GRK1, from photoreceptor inner segments to outer segments. Trafficking of PDE6 and GRK1 to photoreceptor outer segments is impeded in Pde6d knockout mice. In Pde6...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Houbin, Frederick, Jeanne M., Baehr, Wolfgang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081447/
https://ncbi.nlm.nih.gov/pubmed/24664735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_62
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