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Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d(-/-) cones
PrBP/δ, encoded by the Pde6d gene, is an isoprenyl-binding protein that regulates trafficking of isoprenylated proteins, such as PDE6 and GRK1, from photoreceptor inner segments to outer segments. Trafficking of PDE6 and GRK1 to photoreceptor outer segments is impeded in Pde6d knockout mice. In Pde6...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081447/ https://ncbi.nlm.nih.gov/pubmed/24664735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_62 |
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