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Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes

The high incidence of sudden death in heart failure may reflect abnormalities of repolarization and heightened susceptibility to arrhythmogenic early afterdepolarizations (EADs). We hypothesized that overexpression of the human K(+) channel HERG (human ether-a-go-go-related gene) could enhance repol...

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Detalhes bibliográficos
Main Authors: Nuss, H. Bradley, Marbán, Eduardo, Johns, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408140/
https://ncbi.nlm.nih.gov/pubmed/10079110
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