Hypertension in mice lacking 11β-hydroxysteroid dehydrogenase type 2

Deficiency of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) in humans leads to the syndrome of apparent mineralocorticoid excess (SAME), in which cortisol illicitly occupies mineralocorticoid receptors, causing sodium retention, hypokalemia, and hypertension. However, the disorder is usually in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kotelevtsev, Yuri, Brown, Roger W., Fleming, Stewart, Kenyon, Christopher, Edwards, Christopher R.W., Seckl, Jonathan R., Mullins, John J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1999
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC408118/
https://ncbi.nlm.nih.gov/pubmed/10074485
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky