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Decision-making during NHEJ: a network of interactions in human Polμ implicated in substrate recognition and end-bridging

Human Polμ is a DNA polymerase belonging to the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair of double-strand breaks in DNA. Loop1 is a flexible piece of Polμ which has a critical role during terminal transferase and end-joining activities: it acts...

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Detalhes bibliográficos
Main Authors: Martin, Maria Jose, Blanco, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081086/
https://ncbi.nlm.nih.gov/pubmed/24878922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku475
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