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Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice

Parathyroid hormone (PTH) stimulates bone resorption by acting directly on osteoblasts/stromal cells and then indirectly to increase differentiation and function of osteoclasts. PTH acting on osteoblasts/stromal cells increases collagenase gene transcription and synthesis. To assess the role of coll...

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Bibliographic Details
Main Authors: Zhao, Weiguang, Byrne, Michael H., Boyce, Brendan F., Krane, Stephen M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC408105/
https://ncbi.nlm.nih.gov/pubmed/10021460
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