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DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model

Myotonic dystrophy (DM) is the most common form of muscular dystrophy and is caused by expansion of a CTG trinucleotide repeat on human chromosome 19. Patients with DM develop atrioventricular conduction disturbances, the principal cardiac manifestation of this disease. The etiology of the pathophys...

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Autori principali: Berul, Charles I., Maguire, Colin T., Aronovitz, Mark J., Greenwood, Jessica, Miller, Carol, Gehrmann, Josef, Housman, David, Mendelsohn, Michael E., Reddy, Sita
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC408103/
https://ncbi.nlm.nih.gov/pubmed/10021468
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