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Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.

Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3'-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associated with a pathogenic effect of the repeat expans...

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Autors principals: Esther Llagostera, Daniele Catalucci, Luc Marti, Marc Liesa, Marta Camps, Theodore P Ciaraldi, Richard Kondo, Sita Reddy, Wolfgang H Dillmann, Manuel Palacin, Antonio Zorzano, Pilar Ruiz-Lozano, Ramon Gomis, Perla Kaliman
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2007-11-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC2043489?pdf=render
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