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ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics

Functional cell-to-cell variability is ubiquitous in multicellular organisms as well as bacterial populations. Even genetically identical cells of the same cell type can respond differently to identical stimuli. Methods have been developed to analyse heterogeneous populations, e.g., mixture models a...

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Autori principali: Hasenauer, Jan, Hasenauer, Christine, Hucho, Tim, Theis, Fabian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081021/
https://ncbi.nlm.nih.gov/pubmed/24992156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003686
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