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ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics

Functional cell-to-cell variability is ubiquitous in multicellular organisms as well as bacterial populations. Even genetically identical cells of the same cell type can respond differently to identical stimuli. Methods have been developed to analyse heterogeneous populations, e.g., mixture models a...

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Bibliographic Details
Main Authors: Hasenauer, Jan, Hasenauer, Christine, Hucho, Tim, Theis, Fabian J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081021/
https://ncbi.nlm.nih.gov/pubmed/24992156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003686
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