Reactive oxygen species induce MMP12-dependent degradation of collagen 5 and fibronectin to promote the motility of human umbilical cord-derived mesenchymal stem cells

BACKGROUND AND PURPOSE: Reactive oxygen species (ROS) are potent regulators of stem cell behaviour; however, their physiological significance as regards MMP-mediated regulation of the motility of human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) has not been characterized. In the...

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Autors principals: Yun, Seung Pil, Lee, Sei-Jung, Oh, Sang Yub, Jung, Young Hyun, Ryu, Jung Min, Suh, Han Na, Kim, Mi Ok, Oh, Keon Bong, Han, Ho Jae
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080981/
https://ncbi.nlm.nih.gov/pubmed/24627968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12681
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