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Galectin-1 stimulates motility of human umbilical cord blood-derived mesenchymal stem cells by downregulation of smad2/3-dependent collagen 3/5 and upregulation of NF-κB-dependent fibronectin/laminin 5 expression

Galectin-1 (Gal-1) belongs to a family of endogenous lectins with conserved carbohydrate recognition domains binding β-galactosidase sugars and plays a vital role in regulating stem cell functions including determination of cell fate. However, our understanding of the functional roles of Gal-1 in hu...

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Detalhes bibliográficos
Main Authors: Yun, S P, Lee, S-J, Jung, Y H, Han, H J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944255/
https://ncbi.nlm.nih.gov/pubmed/24503541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.3
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