Impact of 5-aza-2′-deoxycytidine and epigallocatechin-3-gallate for induction of human regulatory T cells

The epigenetic regulation of transcription factor genes is critical for T-cell lineage specification. A specific methylation pattern within a conserved region of the lineage specifying transcription factor gene FOXP3, the Treg-specific demethylated region (TSDR), is restricted to regulatory T (Treg)...

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Detalhes bibliográficos
Main Authors: Kehrmann, Jan, Tatura, Roman, Zeschnigk, Michael, Probst-Kepper, Michael, Geffers, Robert, Steinmann, Joerg, Buer, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080954/
https://ncbi.nlm.nih.gov/pubmed/24476360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12261
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