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Quantification of Regulatory T Cells in Septic Patients by Real-Time PCR–Based Methylation Assay and Flow Cytometry

During sepsis, a relative increase of regulatory T (Treg) cells has been reported. Its persistence is associated with lymphocyte anergy, immunoparalysis and a poor prognosis. Currently, an exact quantification of human Treg cells based on protein expression of marker molecules is ambiguous, as these...

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Main Authors: Tatura, Roman, Zeschnigk, Michael, Adamzik, Michael, Probst-Kepper, Michael, Buer, Jan, Kehrmann, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507919/
https://ncbi.nlm.nih.gov/pubmed/23209626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049962
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