Interleukin-8 receptor modulates IgE production and B-cell expansion and trafficking in allergen-induced pulmonary inflammation

We examined the role of the interleukin-8 (IL-8) receptor in a murine model of allergen-induced pulmonary inflammation using mice with a targeted deletion of the murine IL-8 receptor homologue (IL-8r(–/–)). Wild-type (Wt) and IL-8r(–/–) mice were systemically immunized to ovalbumin (OVA) and were ex...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: De Sanctis, George T., MacLean, James A., Qin, Shixin, Wolyniec, Walter W., Grasemann, Hartmut, Yandava, Chandri N., Jiao, Aiping, Noonan, Thomas, Stein-Streilein, Joan, Green, Francis H.Y., Drazen, Jeffrey M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
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Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10021459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4017
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