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Agonists binding nicotinic receptors elicit specific channel-opening patterns at αγ and αδ sites
‘Embryonic’ muscle-type nicotinic acetylcholine receptor channels (nAChRs) bind ligands at interfaces of α- and γ- or δ-subunits. αγ and αδ sites differ in affinity, but their contributions to opening the channel have remained elusive. We compared high-resolution patch clamp currents evoked by epiba...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080934/ https://ncbi.nlm.nih.gov/pubmed/24665094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.267781 |
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