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Polycystins and partners: proposed role in mechanosensitivity

Mutations of the two polycystins, PC1 and PC2, lead to polycystic kidney disease. Polycystins are able to form complexes with numerous families of proteins that have been suggested to participate in mechanical sensing. The proposed role of polycystins and their partners in the kidney primary cilium...

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Détails bibliographiques
Auteurs principaux: Retailleau, Kevin, Duprat, Fabrice
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080931/
https://ncbi.nlm.nih.gov/pubmed/24687583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.271346
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