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A Novel Osteoclast Precursor Cell Line, 4B12, Recapitulates the Features of Primary Osteoclast Differentiation and Function: Enhanced Transfection Efficiency Before and After Differentiation

Osteoclasts are bone-resorbing multinucleated cells differentiated from monocyte/macrophage lineage precursors. A novel osteoclast precursor cell line, 4B12 was established from Mac-1(+)c-Fms(+)RANK(+) cells from calvaria of 14-day-old mouse embryos using immunofluorescence and cell-sorting methods....

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Detalles Bibliográficos
Main Authors: Amano, Shigeru, Sekine, Keisuke, Bonewald, Lynda, Ohmori, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080882/
https://ncbi.nlm.nih.gov/pubmed/19492422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21827
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