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ERK5 Activation Is Essential for Osteoclast Differentiation

The MEK/ERK pathways are critical for controlling cell proliferation and differentiation. In this study, we show that the MEK5/ERK5 pathway participates in osteoclast differentiation. ERK5 was activated by M-CSF, which is one of the essential factors in osteoclast differentiation. Inhibition of MEK5...

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Vydáno v:PLoS One
Hlavní autoři: Amano, Shigeru, Chang, Yu-Tzu, Fukui, Yasuhisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401765/
https://ncbi.nlm.nih.gov/pubmed/25885811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125054
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