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The Transcription Factor Titration Effect Dictates Level of Gene Expression
Models of transcription are often built around a picture of RNA polymerase and transcription factors (TFs) acting on a single copy of a promoter. However, most TFs are shared between multiple genes with varying binding affinities. Beyond that, genes often exist at high copy number; in multiple, iden...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080642/ https://ncbi.nlm.nih.gov/pubmed/24612990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.022 |
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