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Scaling of Gene Expression with Transcription-Factor Fugacity

The proteins associated with gene regulation are often shared between multiple pathways simultaneously. By way of contrast, models in regulatory biology often assume these pathways act independently. We demonstrate a framework for calculating the change in gene expression for the interacting case by...

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Bibliographic Details
Published in:Phys Rev Lett
Main Authors: Weinert, Franz M., Brewster, Robert C., Rydenfelt, Mattias, Phillips, Rob, Kegel, Willem K.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386862/
https://ncbi.nlm.nih.gov/pubmed/25554908
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